221 citations · 932 across the 42 of their papers we have counts for
3 papers · 1 filter
Viral population estimation using pyrosequencing
Nicholas Eriksson, Lior Pachter, Yumi Mitsuya +6
The diversity of virus populations within single infected hosts presents a major difficulty for the natural immune response as well as for vaccine design and antiviral drug therapy…
Towards the Human Genotope
Peter Huggins, Lior Pachter, Bernd Sturmfels
The human genotope is the convex hull of all allele frequency vectors that can be obtained from the genotypes present in the human population. In this paper we take a few initial s…
Epistasis and Shapes of Fitness Landscapes
Niko Beerenwinkel, Lior Pachter, Bernd Sturmfels
The relationship between the shape of a fitness landscape and the underlying gene interactions, or epistasis, has been extensively studied in the two-locus case. Gene interactions…