582 citations · 1.2k across the 19 of their papers we have counts for
3 papers · 1 filter
MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics
Jose A Egea, David Henriques, Thomas Cokelaer +3
Optimization is key to solve many problems in computational biology. Global optimization methods provide a robust methodology, and metaheuristics in particular have proven to be th…
SBML Qualitative Models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools
Claudine Chaouiya, Duncan Berenguier, Sarah M Keating +21
Background: Qualitative frameworks, especially those based on the logical discrete formalism, are increasingly used to model regulatory and signalling networks. A major advantage o…
Large-scale generation of computational models from biochemical pathway maps
Finja Büchel, Nicolas Rodriguez, Neil Swainston +23
Background: Systems biology projects and omics technologies have led to a growing number of biochemical pathway reconstructions. However, mathematical models are still most often c…