582 citations · 1.2k across the 19 of their papers we have counts for
3 papers · 1 filter
FUNKI: Interactive functional footprint-based analysis of omics data
Rosa Hernansaiz-Ballesteros, Christian H. Holland, Aurelien Dugourd +1
Motivation: Omics data, such as transcriptomics or phosphoproteomics, are broadly used to get a snap-shot of the molecular status of cells. In particular, changes in omics can be u…
Inferring clonal composition from multiple tumor biopsies
Matteo Manica, Hyunjae Ryan Kim, Roland Mathis +14
Explicit accounting for copy number alterations can dramatically improve mutation frequency estimates, leading to more accurate phylogeny reconstructions and subclone characterizat…
Machine learning prediction of cancer cell sensitivity to drugs based on genomic and chemical properties
Michael P. Menden, Francesco Iorio, Mathew Garnett +4
Predicting the response of a specific cancer to a therapy is a major goal in modern oncology that should ultimately lead to a personalised treatment. High-throughput screenings of…