2 citations · 2 across the 5 of their papers we have counts for
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q-bio.BM2008
Emergence of mutationally robust proteins in a microscopic model of evolution
Konstantin B. Zeldovich, Eugene I. Shakhnovich
The ability to absorb mutations while retaining structure and function, or mutational robustness, is a remarkable property of natural proteins. In this Letter, we use a computation…
q-bio.CB2008
Diversity against adversity: How adaptive immunity evolves potent antibodies
Muyoung Heo, Konstantin B. Zeldovich, Eugene I. Shakhnovich
How does immune system evolve functional proteins - potent antibodies - in such a short time? We address this question using a microscopic, protein-level, sequence-based model of h…