104 citations · 105 across the 7 of their papers we have counts for
4 papers · 1 filter
Predicting genetic interactions from Boolean models of biological networks
Laurence Calzone, Emmanuel Barillot, Andrei Zinovyev
Genetic interaction can be defined as a deviation of the phenotypic quantitative effect of a double gene mutation from the effect predicted from single mutations using a simple (e.…
NaviCell: a web-based environment for navigation, curation and maintenance of large molecular interaction maps
Inna Kuperstein, David PA Cohen, Stuart Pook +3
Molecular biology knowledge can be systematically represented in a computer-readable form as a comprehensive map of molecular interactions. There exist a number of maps of molecula…
Cell death and life in cancer: mathematical modeling of cell fate decisions
Andrei Zinovyev, Simon Fourquet, Laurent Tournier +2
Tumor development is characterized by a compromised balance between cell life and death decision mechanisms, which are tighly regulated in normal cells. Understanding this process…
Continuous time Boolean modeling for biological signaling: application of Gillespie algorithm
Gautier Stoll, Eric Viara, Emmanuel Barillot +1
This article presents an algorithm that allows modeling of biological networks in a qualitative framework with continuous time. Mathematical modeling is used as a systems biology t…