95 citations · 214 across the 11 of their papers we have counts for
3 papers · 1 filter
Mechanism, scaling and rates of protein aggregation from in vivo measurements
Georg Meisl, Alexander J Dear, Thomas CT Michaels +1
The formation and proliferation of protein aggregates play a central role in a number of devastating neuro-degenerative diseases. Many experimental studies indicate that the abilit…
Spatial control of irreversible protein aggregation
Christoph A. Weber, Thomas C. T. Michaels, L. Mahadevan
Liquid cellular compartments spatially segregate from the cytoplasm and can regulate aberrant protein aggregation, a process linked to several medical conditions, including Alzheim…
Reaction rate theory for supramolecular kinetics: application to protein aggregation
Thomas C. T. Michaels, Lucie X. Liu, Samo Curk +3
Probing the reaction mechanisms of supramolecular processes in soft- and biological matter, such as protein aggregation, is inherently challenging. These processes emerge from the…