45 citations · 105 across the 23 of their papers we have counts for
3 papers · 1 filter
Single-cell 3D genome reconstruction in the haploid setting using rigidity theory
Sean Dewar, Georg Grasegger, Kaie Kubjas +2
This article considers the problem of 3-dimensional genome reconstruction for single-cell data, and the uniqueness of such reconstructions in the setting of haploid organisms. We c…
3D genome reconstruction from partially phased Hi-C data
Diego Cifuentes, Jan Draisma, Oskar Henriksson +2
The 3-dimensional (3D) structure of the genome is of significant importance for many cellular processes. In this paper, we study the problem of reconstructing the 3D structure of c…
Identifying 3D Genome Organization in Diploid Organisms via Euclidean Distance Geometry
Anastasiya Belyaeva, Kaie Kubjas, Lawrence J. Sun +1
The spatial organization of the DNA in the cell nucleus plays an important role for gene regulation, DNA replication, and genomic integrity. Through the development of chromosome c…