62 citations · 197 across the 13 of their papers we have counts for
5 papers · 1 filter
Universal principles of cell population growth follow from local contact inhibition
Gregory J. Kimmel, Sadegh Marzban, Mehdi Damaghi +4
Cancer cell populations often exhibit remarkably similar growth laws despite their heterogeneity. Explanations of universal cell population growth remain partly unresolved to this…
Evolutionary dynamics of competing phenotype-structured populations in periodically fluctuating environments
Aleksandra Ardaševa, Robert A. Gatenby, Alexander R. A. Anderson +3
Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading thr…
The evolution of carrying capacity in constrained and expanding tumour cell populations
Philip Gerlee, Alexander R. A. Anderson
Cancer cells are known to modify their micro-environment such that it can sustain a larger population, or, in ecological terms, they construct a niche which increases the carrying…
Evolution of intratumoral phenotypic heterogeneity: the role of trait inheritance
Jill Gallaher, Alexander R. A. Anderson
A tumor can be thought of as an ecosystem, which critically means that we cannot just consider it as a collection of mutated cells but more as a complex system of many interacting…
A Markov chain model of evolution in asexually reproducing populations: insight and analytical tractability in the evolutionary process
Daniel Nichol, Peter Jeavons, Robert Bonomo +5
The evolutionary process has been modelled in many ways using both stochastic and deterministic models. We develop an algebraic model of evolution in a population of asexually repr…