31 citations · 40 across the 7 of their papers we have counts for
4 papers · 1 filter
Striking a balance with Recon 2.1
Kieran Smallbone
Recon 2 is a highly curated reconstruction of the human metabolic network. Whilst the network is state of the art, it has shortcomings, including the presence of unbalanced reactio…
Metabolic Control Analysis: Rereading Reder
Kieran Smallbone
Metabolic control analysis is a biochemical formalism defined by Kacser and Burns in 1973, and given firm mathematical basis by Reder in 1988. The algorithm defined by Reder for ca…
Standardized network reconstruction of CHO cell metabolism
Kieran Smallbone
We have created a genome-scale network reconstruction of chinese hamster ovary (CHO) cell metabolism. Existing reconstructions were improved in terms of annotation standards, to fa…
Standardized network reconstruction of E. coli metabolism
Kieran Smallbone
We have created a genome-scale network reconstruction of Escherichia coli metabolism. Existing reconstructions were improved in terms of annotation standards, to facilitate their s…