31 citations · 40 across the 7 of their papers we have counts for
8 papers
BioPreDyn-bench: benchmark problems for kinetic modelling in systems biology
Alejandro F Villaverde, David Henriques, Kieran Smallbone +10
Dynamic modelling is one of the cornerstones of systems biology. Many research efforts are currently being invested in the development and exploitation of large-scale kinetic model…
A robust and efficient method for estimating enzyme complex abundance and metabolic flux from expression data
Brandon Barker, Narayanan Sadagopan, Yiping Wang +5
A major theme in constraint-based modeling is unifying experimental data, such as biochemical information about the reactions that can occur in a system or the composition and loca…
Striking a balance with Recon 2.1
Kieran Smallbone
Recon 2 is a highly curated reconstruction of the human metabolic network. Whilst the network is state of the art, it has shortcomings, including the presence of unbalanced reactio…
Metabolic Control Analysis: Rereading Reder
Kieran Smallbone
Metabolic control analysis is a biochemical formalism defined by Kacser and Burns in 1973, and given firm mathematical basis by Reder in 1988. The algorithm defined by Reder for ca…
Standardized network reconstruction of CHO cell metabolism
Kieran Smallbone
We have created a genome-scale network reconstruction of chinese hamster ovary (CHO) cell metabolism. Existing reconstructions were improved in terms of annotation standards, to fa…
Standardized network reconstruction of E. coli metabolism
Kieran Smallbone
We have created a genome-scale network reconstruction of Escherichia coli metabolism. Existing reconstructions were improved in terms of annotation standards, to facilitate their s…