15 papers
TrinityDNA: A Bio-Inspired Foundational Model for Efficient Long-Sequence DNA Modeling
Qirong Yang, Yucheng Guo, Zicheng Liu +7
The modeling of genomic sequences presents unique challenges due to their length and structural complexity. Traditional sequence models struggle to capture long-range dependencies…
The Trinity of Consistency as a Defining Principle for General World Models
Jingxuan Wei, Siyuan Li, Yuhang Xu +21
The construction of World Models capable of learning, simulating, and reasoning about objective physical laws constitutes a foundational challenge in the pursuit of Artificial Gene…
Multimodal Regression for Enzyme Turnover Rates Prediction
Bozhen Hu, Cheng Tan, Siyuan Li +4
The enzyme turnover rate is a fundamental parameter in enzyme kinetics, reflecting the catalytic efficiency of enzymes. However, enzyme turnover rates remain scarce across most org…
SketchAgent: Generating Structured Diagrams from Hand-Drawn Sketches
Cheng Tan, Qi Chen, Jingxuan Wei +6
Hand-drawn sketches are a natural and efficient medium for capturing and conveying ideas. Despite significant advancements in controllable natural image generation, translating fre…
AlphaFold Database Debiasing for Robust Inverse Folding
Cheng Tan, Zhenxiao Cao, Zhangyang Gao +3
The AlphaFold Protein Structure Database (AFDB) offers unparalleled structural coverage at near-experimental accuracy, positioning it as a valuable resource for data-driven protein…
Mitigating Prior Shape Bias in Point Clouds via Differentiable Center Learning
Zhe Li, Xiying Wang, Jinglin Zhao +3
Masked autoencoding and generative pretraining have achieved remarkable success in computer vision and natural language processing, and more recently, they have been extended to th…