11 citations · 13 across the 7 of their papers we have counts for
3 papers · 1 filter
FastLORS: Joint Modeling for eQTL Mapping in R
Jacob Rhyne, Eric Chi, Jung-Ying Tzeng +1
Yang et al. (2013) introduced LORS, a method that jointly models the expression of genes, SNPs, and hidden factors for eQTL mapping. LORS solves a convex optimization problem and h…
eQTL Mapping via Effective SNP Ranking and Screening
Jacob Rhyne, Jung-Ying Tzeng, Teng Zhang +1
Genome-wide eQTL mapping explores the relationship between gene expression values and DNA variants to understand genetic causes of human disease. Due to the large number of genes a…
Gene-level pharmacogenetic analysis on survival outcomes using gene-trait similarity regression
Jung-Ying Tzeng, Wenbin Lu, Fang-Chi Hsu
Gene/pathway-based methods are drawing significant attention due to their usefulness in detecting rare and common variants that affect disease susceptibility. The biological mechan…