11 citations · 13 across the 7 of their papers we have counts for
7 papers
SEAGLE: A Scalable Exact Algorithm for Large-Scale Set-Based GxE Tests in Biobank Data
Jocelyn T. Chi, Ilse C. F. Ipsen, Tzu-Hung Hsiao +5
The explosion of biobank data offers immediate opportunities for gene-environment (GxE) interaction studies of complex diseases because of the large sample sizes and the rich colle…
The Robust Kernel Association Test
Kara Martinez, Arnab Maity, Robert Yolken +2
Testing the association between SNP effects and a response is a common task. Such tests are often carried out through kernel machine methods based on least squares, such as the Seq…
FastLORS: Joint Modeling for eQTL Mapping in R
Jacob Rhyne, Eric Chi, Jung-Ying Tzeng +1
Yang et al. (2013) introduced LORS, a method that jointly models the expression of genes, SNPs, and hidden factors for eQTL mapping. LORS solves a convex optimization problem and h…
Efficient Signal Inclusion With Genomic Applications
X. Jessie Jeng, Teng Zhang, Jung-Ying Tzeng
This paper addresses the challenge of efficiently capturing a high proportion of true signals for subsequent data analyses when sample sizes are relatively limited with respect to…
eQTL Mapping via Effective SNP Ranking and Screening
Jacob Rhyne, Jung-Ying Tzeng, Teng Zhang +1
Genome-wide eQTL mapping explores the relationship between gene expression values and DNA variants to understand genetic causes of human disease. Due to the large number of genes a…
Gene-level pharmacogenetic analysis on survival outcomes using gene-trait similarity regression
Jung-Ying Tzeng, Wenbin Lu, Fang-Chi Hsu
Gene/pathway-based methods are drawing significant attention due to their usefulness in detecting rare and common variants that affect disease susceptibility. The biological mechan…