58 citations · 368 across the 11 of their papers we have counts for
4 papers · 1 filter
Networked Enzymatic Logic Gates with Filtering: New Theoretical Modeling Expressions and Their Experimental Application
Vladimir Privman, Oleksandr Zavalov, Lenka Halamkova +3
We report the first study of a network of connected enzyme-catalyzed reactions, with added chemical and enzymatic processes that incorporate the recently developed biochemical filt…
Extended Linear Response for Bioanalytical Applications Using Multiple Enzymes
Vladimir Privman, Oleksandr Zavalov, Aleksandr Simonian
We develop a framework for optimizing a novel approach to extending the linear range of bioanalytical systems and biosensors by utilizing two enzymes with different kinetic respons…
Enzyme-Based Logic: OR Gate with Double-Sigmoid Filter Response
Oleksandr Zavalov, Vera Bocharova, Vladimir Privman +1
The first realization of a biomolecular OR gate function with double-sigmoid response (sigmoid in both inputs) is reported. Two chemical inputs activate the enzymatic gate processe…
Enzyme-Based Logic Analysis of Biomarkers at Physiological Concentrations: AND Gate with Double-Sigmoid "Filter" Response
Jan Halamek, Oleksandr Zavalov, Lenka Halamkova +3
We report the first realization of a biomolecular AND gate function with double-sigmoid response (sigmoid in both inputs). Two enzyme biomarker inputs activate the gate output sign…