339 citations · 525 across the 7 of their papers we have counts for
3 papers · 1 filter
A reproducible effect size is more useful than an irreproducible hypothesis test to analyze high throughput sequencing datasets
Andrew D. Fernandes, Michael T. H. Q. Vu, Lisa-Monique Edward +2
Motivation: P values derived from the null hypothesis significance testing framework are strongly affected by sample size, and are known to be irreproducible in underpowered studie…
XORRO: Rapid Paired-End Read Overlapper
Russell J. Dickson, Gregory B. Gloor
Background: Computational analysis of next-generation sequencing data is outpaced by data generation in many cases. In one such case, paired-end reads can be produced from the Illu…
Microbiome profiling by Illumina sequencing of combinatorial sequence-tagged PCR products
Gregory B. Gloor, Ruben Hummelen, Jean M. Macklaim +4
We developed a low-cost, high-throughput microbiome profiling method that uses combinatorial sequence tags attached to PCR primers that amplify the rRNA V6 region. Amplified PCR pr…