96 citations · 617 across the 17 of their papers we have counts for
6 papers · 1 filter
Networked Enzymatic Logic Gates with Filtering: New Theoretical Modeling Expressions and Their Experimental Application
Vladimir Privman, Oleksandr Zavalov, Lenka Halamkova +3
We report the first study of a network of connected enzyme-catalyzed reactions, with added chemical and enzymatic processes that incorporate the recently developed biochemical filt…
Bioinspired Associative Memory System Based on Enzymatic Cascades
Kevin MacVittie, Jan Halamek, Vladimir Privman +1
A biomolecular system representing the first realization of associative memory based on enzymatic reactions in vitro has been designed. The system demonstrated "training" and "forg…
Realization of Associative Memory in an Enzymatic Process: Towards Biomolecular Networks with Learning and Unlearning Functionalities
Vera Bocharova, Kevin MacVittie, Soujanya Chinnapareddy +3
We report a realization of an associative memory signal/information processing system based on simple enzyme-catalyzed biochemical reactions. Optically detected chemical output is…
Enzyme-Based Logic Analysis of Biomarkers at Physiological Concentrations: AND Gate with Double-Sigmoid "Filter" Response
Jan Halamek, Oleksandr Zavalov, Lenka Halamkova +3
We report the first realization of a biomolecular AND gate function with double-sigmoid response (sigmoid in both inputs). Two enzyme biomarker inputs activate the gate output sign…
Optimization of Enzymatic Logic Gates and Networks for Noise Reduction and Stability
Mary A. Arugula, Jan Halamek, Evgeny Katz +4
Biochemical computing attempts to process information with biomolecules and biological objects. In this work we review our results on analysis and optimization of single biochemica…
Network Analysis of Biochemical Logic for Noise Reduction and Stability: A System of Three Coupled Enzymatic AND Gates
Vladimir Privman, Mary A. Arugula, Jan Halamek +2
We develop an approach aimed at optimizing the parameters of a network of biochemical logic gates for reduction of the "analog" noise buildup. Experiments for three coupled enzymat…