602 citations · 2.2k across the 50 of their papers we have counts for
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q-bio.MN2004★ 18 cited
Modeling network dynamics: the lac operon, a case study
J. M. G. Vilar, C. C. Guet, S. Leibler
We use the lac operon in Escherichia coli as a prototype system to illustrate the current state, applicability, and limitations of modeling the dynamics of cellular networks. We in…
q-bio.SC2004
DNA looping and physical constraints on transcription regulation
Jose M. G. Vilar, Stanislas Leibler
DNA looping participates in transcriptional regulation, for instance, by allowing distal binding sites to act synergistically. Here we study this process and compare different regu…