18 citations · 29 across the 3 of their papers we have counts for
4 papers · 1 filter
Modelling diffusional transport in the interphase cell nucleus
Annika Wedemeier, Holger Merlitz, Chen-Xu Wu +1
In this paper a lattice model for diffusional transport of particles in the interphase cell nucleus is proposed. Dense networks of chromatin fibers are created by three different m…
Facilitated diffusion of DNA-binding proteins: Simulation of large systems
Holger Merlitz, Konstantin V. Klenin, Chen-Xu Wu +1
The recently introduced method of excess collisions (MEC) is modified to estimate diffusion-controlled reaction times inside systems of arbitrary size. The resulting MEC-E equation…
Facilitated diffusion of DNA-binding proteins: Efficient simulation with the method of excess collisions (MEC)
Holger Merlitz, Konstantin V. Klenin, Chen-Xu Wu +1
In this paper, a new method to efficiently simulate diffusion controlled second order chemical reactions is derived and applied to site-specific DNA-binding proteins. The protein e…
Facilitated diffusion of DNA-binding proteins
Konstantin V. Klenin, Holger Merlitz, Joerg Langowski +1
The diffusion-controlled limit of reaction times for site-specific DNA-binding proteins is derived from first principles. We follow the generally accepted concept that a protein pr…