activity
20052011
most citedFacilitated diffusion of DNA-binding proteins

71 citations · 185 across the 7 of their papers we have counts for

collaborators

7 papers

physics.optics2011★ 53 cited

FPGA implementation of a 32x32 autocorrelator array for analysis of fast image series

Jan Buchholz, Jan Wolfgang Krieger, Gábor Mocsár +5

With the evolving technology in CMOS integration, new classes of 2D-imaging detectors have recently become available. In particular, single photon avalanche diode (SPAD) arrays all…

physics.bio-ph2009★ 22 cited

How proteins squeeze through polymer networks: a Cartesian lattice study

Annika Wedemeier, Holger Merlitz, Chen-Xu Wu +1

In this paper a lattice model for the diffusional transport of particles in the interphase cell nucleus is proposed. The dynamic behaviour of single chains on the lattice is invest…

physics.bio-ph2007★ 18 cited

Modelling diffusional transport in the interphase cell nucleus

Annika Wedemeier, Holger Merlitz, Chen-Xu Wu +1

In this paper a lattice model for diffusional transport of particles in the interphase cell nucleus is proposed. Dense networks of chromatin fibers are created by three different m…

physics.bio-ph2006★ 11 cited

Facilitated diffusion of DNA-binding proteins: Simulation of large systems

Holger Merlitz, Konstantin V. Klenin, Chen-Xu Wu +1

The recently introduced method of excess collisions (MEC) is modified to estimate diffusion-controlled reaction times inside systems of arbitrary size. The resulting MEC-E equation…

physics.bio-ph2005★ 10 cited

Facilitated diffusion of DNA-binding proteins: Efficient simulation with the method of excess collisions (MEC)

Holger Merlitz, Konstantin V. Klenin, Chen-Xu Wu +1

In this paper, a new method to efficiently simulate diffusion controlled second order chemical reactions is derived and applied to site-specific DNA-binding proteins. The protein e…

q-bio.BM2005

In silicio stretching of chromatin

Frank Aumann, Filip Lankas, Maiwen Caudron +1

We present Monte-Carlo (MC) simulations of the stretching of a single 30 nm chromatin fiber. The model approximates the DNA by a flexible polymer chain with Debye-Hückel electrosta…