125 citations · 1.2k across the 46 of their papers we have counts for
46 papers
Mechanisms of DNA-mediated allostery
Midas Segers, Aderik Voorspoels, Takahiro Sakaue +1
Proteins often regulate their activities via allostery - or action at a distance - in which the binding of a ligand at one binding site influences the affinity for another ligand a…
Rigid Base Biasing in Molecular Dynamics enables enhanced sampling of DNA conformations
Aderik Voorspoels, Jocelyne Vreede, Enrico Carlon
All-atom simulations have become increasingly popular to study conformational and dynamical properties of nucleic acids as they are accurate and provide high spatial and time resol…
Equilibrium Fluctuations of DNA Plectonemes
Enrico Skoruppa, Enrico Carlon
Plectonemes are intertwined helically looped domains which form when a DNA molecule is supercoiled, i.e. over- or under-wounded. They are ubiquitous in cellular DNA and their physi…
Mechanical properties of Nucleic Acids and the non-local Twistable Wormlike Chain model
Midas Segers, Aderik Voorspoels, Takahiro Sakaue +1
Mechanical properties of nucleic acids play an important role in many biological processes which often involve physical deformations of these molecules. At sufficiently long length…
Comment on "Flexibility of short DNA helices with finite-length effect: From base pairs to tens of base pairs"
Midas Segers, Enrico Skoruppa, Jan A. Stevens +3
While analyzing the persistence length of DNA atomistic simulations Wu et al. [J. Chem. Phys. 142, 125103 (2015)] introduced an empirical formula to account for the observed length…
Length scale dependent elasticity in DNA from coarse-grained and all-atom models
Enrico Skoruppa, Aderik Voorspoels, Jocelyne Vreede +1
The mechanical properties of DNA are typically described by elastic theories with purely local couplings (on-site models). We discuss and analyze coarse-grained (oxDNA) and all-ato…