7 citations · 26 across the 16 of their papers we have counts for
3 papers · 1 filter
Semiconservative Replication in the Quasispecies Model
Emmanuel Tannenbaum, Eric J. Deeds, Eugene I. Shakhnovich
This paper extends Eigen's quasispecies equations to account for the semiconservative nature of DNA replication. We solve the equations in the limit of infinite sequence length for…
The Error and Repair Catastrophes: A Two-Dimensional Phase Diagram in the Quasispecies Model
Emmanuel Tannenbaum, Eugene I. Shakhnovich
This paper develops a two gene, single fitness peak model for determining the equilibrium distribution of genotypes in a unicellular population which is capable of genetic damage r…
Equilibrium Distribution of Mutators in the Single Fitness Peak Model
Emmanuel Tannenbaum, Eric Deeds, Eugene I. Shakhnovich
This paper develops an analytically tractable model for determining the equilibrium distribution of mismatch repair deficient strains in unicellular populations. The approach is ba…