1 citations · 1 across the 4 of their papers we have counts for
5 papers
Sexual replication in the quasispecies model
Emmanuel Tannenbaum
This paper develops a simplified model for sexual replication within the quasispecies formalism. We assume that the genomes of the replicating organisms are two-chromosomed and dip…
An RNA-centered view of eukaryotic cells
Emmanuel Tannenbaum
Emerging evidence suggests that the introns and intergenic sequences of the genomes of higher eukaryotes (the ``junk'' DNA) codes for a vast, RNA-based, genetic regulatory network.…
Semiconservative replication in the quasispecies model II: Generalization to arbitrary lesion repair probabilities
Emmanuel Tannenbaum, James L. Sherley, Eugene I. Shakhnovich
This paper extends the semiconservative quasispecies equations to account for arbitrary post-replication lesion repair efficiency. Such an extension could be an important tool for…
Imperfect DNA Repair and the Error Catastrophe
Yisroel Brumer, Emmanuel Tannenbaum, Eugene I. Shakhnovich
In this Letter, we extend the semiconservative quasispecies equations to incorporate imperfect DNA lesion repair. We study the equilibrium behavior of this model in the limit of in…
A PDE-Based Approach to Classical Phase-Space Deformations
Emmanuel Tannenbaum
This paper presents a PDE-based approach to finding an optimal canonical basis with which to represent a nearly integrable Hamiltonian. The idea behind the method is to continuousl…