73 citations · 79 across the 2 of their papers we have counts for
2 papers
q-bio.PE2012★ 73 cited
Genotype to phenotype mapping and the fitness landscape of the E. coli lac promoter
Jakub Otwinowski, Ilya Nemenman
Genotype-to-phenotype maps and the related fitness landscapes that include epistatic interactions are difficult to measure because of their high dimensional structure. Here we cons…
q-bio.PE2010★ 6 cited
Speeding up evolutionary search by small fitness fluctuations
Jakub Otwinowski, Sorin Tanase-Nicola, Ilya Nemenman
We consider a fixed size population that undergoes an evolutionary adaptation in the weak mutuation rate limit, which we model as a biased Langevin process in the genotype space. W…