129 citations · 129 across the 1 of their papers we have counts for
3 papers
q-bio.MN2012★ 129 cited
Epigenetic landscapes explain partially reprogrammed cells and identify key reprogramming genes
Alex H. Lang, Hu Li, James J. Collins +1
A common metaphor for describing development is a rugged "epigenetic landscape" where cell fates are represented as attracting valleys resulting from a complex regulatory network.…
physics.bio-ph2001
Designer Gene Networks: Towards Fundamental Cellular Control
Jeff Hasty, Farren Isaacs, Milos Dolnik +2
The engineered control of cellular function through the design of synthetic genetic networks is becoming plausible. Here we show how a naturally occurring network can be used as a…
physics.bio-ph2000
Noise-based switches and amplifiers for gene expression
Jeff Hasty, Joel Pradines, Milos Dolnik +1
The regulation of cellular function is often controlled at the level of gene transcription. Such genetic regulation usually consists of interacting networks, whereby gene products…