48 citations · 49 across the 2 of their papers we have counts for
2 papers
q-bio.MN2014★ 1 cited
Detecting the Escherichia coli metabolic backbone
Oriol Güell, Francesc Sagués, M. Ángeles Serrano
The heterogeneity of reaction fluxes present in a metabolic network within a single flux state can be exploited to construct the so-called backbone as a reduced version of metaboli…
q-bio.MN2013★ 48 cited
Essential plasticity and redundancy of metabolism unveiled by synthetic lethality analysis
Oriol Güell, Francesc Sagués, M. Ángeles Serrano
We unravel how functional plasticity and redundancy are essential mechanisms underlying the ability to survive of metabolic networks. We perform an exhaustive computational screeni…