activity
20102015
most citedLength of adaptive walk on uncorrelated and correlated fitness landscapes

7 citations · 19 across the 4 of their papers we have counts for

collaborators

6 papers

q-bio.PE2015★ 5 cited

Exploiting the adaptation dynamics to predict the distribution of beneficial fitness effects

Sona John, Sarada Seetharaman

Adaptation of asexual populations is driven by beneficial mutations and therefore the dynamics of this process, besides other factors, depend on the distribution of beneficial fitn…

q-bio.PE2014★ 7 cited

Length of adaptive walk on uncorrelated and correlated fitness landscapes

Sarada Seetharaman, Kavita Jain

We consider the adaptation dynamics of an asexual population that walks uphill on a rugged fitness landscape which is endowed with large number of local fitness peaks. We work in a…

q-bio.PE2013

Adaptive walks and distribution of beneficial fitness effects

Sarada Seetharaman, Kavita Jain

We study the adaptation dynamics of a maladapted asexual population on rugged fitness landscapes with many local fitness peaks. The distribution of beneficial fitness effects is as…

q-bio.PE2011★ 7 cited

Nonlinear deterministic equations in biological evolution

Kavita Jain, Sarada Seetharaman

We review models of biological evolution in which the population frequency changes deterministically with time. If the population is self-replicating, although the equations for si…

q-bio.PE2011

Multiple adaptive substitutions during evolution in novel environments

Kavita Jain, Sarada Seetharaman

We consider an asexual population under strong selection-weak mutation conditions evolving on rugged fitness landscapes with many local fitness peaks. Unlike the previous studies i…

q-bio.PE2010

Evolutionary dynamics on strongly correlated fitness landscapes

Sarada Seetharaman, Kavita Jain

We study the evolutionary dynamics of a maladapted population of self-replicating sequences on strongly correlated fitness landscapes. Each sequence is assumed to be composed of bl…