867 citations · 1.9k across the 5 of their papers we have counts for
3 papers · 1 filter
Spatial model predicts dispersal and cell turnover cause reduced intra-tumor heterogeneity
Bartlomiej Waclaw, Ivana Bozic, Meredith E. Pittman +3
Most cancers in humans are large, measuring centimeters in diameter, composed of many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as a resul…
Accumulation of driver and passenger mutations during tumor progression
Ivana Bozic, Tibor Antal, Hisashi Ohtsuki +7
Major efforts to sequence cancer genomes are now occurring throughout the world. Though the emerging data from these studies are illuminating, their reconciliation with epidemiolog…
Genetic progression and the waiting time to cancer
Niko Beerenwinkel, Tibor Antal, David Dingli +5
Cancer results from genetic alterations that disturb the normal cooperative behavior of cells. Recent high-throughput genomic studies of cancer cells have shown that the mutational…