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most citedFundamental limits on the accuracy of demographic inference based on the sample frequency spectrum

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q-bio.PE2017

Geometry of the sample frequency spectrum and the perils of demographic inference

Zvi Rosen, Anand Bhaskar, Sebastien Roch +1

The sample frequency spectrum (SFS), which describes the distribution of mutant alleles in a sample of DNA sequences, is a widely used summary statistic in population genetics. The…