115 citations · 1k across the 31 of their papers we have counts for
6 papers · 1 filter
General triallelic frequency spectrum under demographic models with variable population size
Paul A. Jenkins, Jonas W. Mueller, Yun S. Song
It is becoming routine to obtain datasets on DNA sequence variation across several thousands of chromosomes, providing unprecedented opportunity to infer the underlying biological…
SMaSH: A Benchmarking Toolkit for Human Genome Variant Calling
Ameet Talwalkar, Jesse Liptrap, Julie Newcomb +7
Motivation: Computational methods are essential to extract actionable information from raw sequencing data, and to thus fulfill the promise of next-generation sequencing technology…
A novel spectral method for inferring general diploid selection from time series genetic data
Matthias Steinrücken, Anand Bhaskar, Yun S. Song
The increased availability of time series genetic variation data from experimental evolution studies and ancient DNA samples has created new opportunities to identify genomic regio…
Descartes' rule of signs and the identifiability of population demographic models from genomic variation data
Anand Bhaskar, Yun S. Song
The sample frequency spectrum (SFS) is a widely-used summary statistic of genomic variation in a sample of homologous DNA sequences. It provides a highly efficient dimensional redu…
Distortion of genealogical properties when the sample is very large
Anand Bhaskar, Andrew G. Clark, Yun S. Song
Study sample sizes in human genetics are growing rapidly, and in due course it will become routine to analyze samples with hundreds of thousands if not millions of individuals. In…
The influence of relatives on the efficiency and error rate of familial searching
Rori V. Rohlfs, Erin Murphy, Yun S. Song +1
We investigate the consequences of adopting the criteria used by the state of California, as described by Myers et al. (2011), for conducting familial searches. We carried out a si…