68 citations · 120 across the 6 of their papers we have counts for
4 papers · 1 filter
De novo inference of diversity genes and analysis of non-canonical V(DD)J recombination in immunoglobulins
Yana Safonova, Pavel A. Pevzner
The V(D)J recombination forms the immunoglobulin genes by joining the variable (V), diversity (D), and joining (J) germline genes. Since variations in germline genes have been link…
Reconstructing antibody repertoires from error-prone immunosequencing datasets
Alexander Shlemov, Sergey Bankevich, Andrey Bzikadze +3
Transforming error-prone immunosequencing datasets into antibody repertoires is a fundamental problem in immunogenomics, and a prerequisite for studies of immune responses. Althoug…
metaSPAdes: a new versatile de novo metagenomics assembler
Sergey Nurk, Dmitry Meleshko, Anton Korobeynikov +1
While metagenomics has emerged as a technology of choice for analyzing bacterial populations, assembly of metagenomic data remains difficult thus stifling biological discoveries. m…
Limited Lifespan of Fragile Regions in Mammalian Evolution
Max A. Alekseyev, Pavel A. Pevzner
An important question in genome evolution is whether there exist fragile regions (rearrangement hotspots) where chromosomal rearrangements are happening over and over again. Althou…