10 citations · 16 across the 10 of their papers we have counts for
5 papers · 1 filter
DMseg: a Python algorithm for de novo detection of differentially or variably methylated regions
Xiaoyu Wang, Ming Yu, William Grady +3
Detecting and assessing statistical significance of differentially methylated regions (DMRs) is a fundamental task in methylome association studies. While the average differential…
Incorporating increased variability in testing for cancer DNA methylation
James Y. Dai, Heng Chen, Xiaoyu Wang +4
Cancer development is associated with aberrant DNA methylation, including increased stochastic variability. Statistical tests for discovering cancer methylation biomarkers have foc…
Fisher-Pitman permutation tests based on nonparametric Poisson mixtures with application to single cell genomics
Zhen Miao, Weihao Kong, Ramya Korlakai Vinayak +2
This paper investigates the theoretical and empirical performance of Fisher-Pitman-type permutation tests for assessing the equality of unknown Poisson mixture distributions. Build…
Gaussian process regression for survival time prediction with genome-wide gene expression
Aaron J. Molstad, Li Hsu, Wei Sun
Predicting the survival time of a cancer patient based on his/her genome-wide gene expression remains a challenging problem. For certain types of cancer, the effects of gene expres…
PenPC: A Two-step Approach to Estimate the Skeletons of High Dimensional Directed Acyclic Graphs
Min Jin Ha, Wei Sun, Jichun Xie
Estimation of the skeleton of a directed acyclic graph (DAG) is of great importance for understanding the underlying DAG and causaleffects can be assessed from the skeleton when th…