74 citations · 461 across the 38 of their papers we have counts for
4 papers · 1 filter
Simultaneous detection and estimation of trait associations with genomic phenotypes
Jean Morrison, Noah Simon, Daniela Witten
Genomic phenotypes, such as DNA methylation and chromatin accessibility, can be used to characterize the transcriptional and regulatory activity of DNA within a cell. Recent techno…
Nonparametric Regression with Adaptive Truncation via a Convex Hierarchical Penalty
Asad Haris, Ali Shojaie, Noah Simon
We consider the problem of non-parametric regression with a potentially large number of covariates. We propose a convex, penalized estimation framework that is particularly well-su…
Graphical Models for Zero-Inflated Single Cell Gene Expression
Andrew McDavid, Raphael Gottardo, Noah Simon +1
Bulk gene expression experiments relied on aggregations of thousands of cells to measure the average expression in an organism. Advances in microfluidic and droplet sequencing now…
Graphical Models for Discrete and Continuous Data
Rui Zhuang, Noah Simon, Johannes Lederer
We introduce a general framework for undirected graphical models. It generalizes Gaussian graphical models to a wide range of continuous, discrete, and combinations of different ty…