2 papers
stat.ME2022
Accounting for Inconsistent Use of Covariate Adjustment in Group Sequential Trials
Marlena S. Bannick, Sonya L. Heltshe, Noah Simon
Group sequential designs in clinical trials allow for interim efficacy and futility monitoring. Adjustment for baseline covariates can increase power and precision of estimated eff…
stat.AP2021
The Future will be Different than Today: Model Evaluation Considerations when Developing Translational Clinical Biomarker
Yichen Lu, Jane Fridlyand, Tiffany Tang +3
Finding translational biomarkers stands center stage of the future of personalized medicine in healthcare. We observed notable challenges in identifying robust biomarkers as some w…