302 citations · 2.5k across the 74 of their papers we have counts for
4 papers · 1 filter
Green function of correlated genes in a minimal mechanical model of protein evolution
Sandipan Dutta, Jean-Pierre Eckmann, Albert Libchaber +1
The function of proteins arises from cooperative interactions and rearrangements of their amino acids, which exhibit large-scale dynamical modes. Long-range correlations have also…
A simple model for the evolution of molecular codes driven by the interplay of accuracy, diversity and cost
Tsvi Tlusty
Molecular codes translate information written in one type of molecules into another molecular language. We introduce a simple model that treats molecular codes as noisy information…
A model for the emergence of the genetic code as a transition in a noisy information channel
Tsvi Tlusty
The genetic code maps the sixty-four nucleotide triplets (codons) to twenty amino-acids. Some argue that the specific form of the code with its twenty amino-acids might be a 'froze…
Casting Polymer Nets to Optimize Noisy Molecular Codes
Tsvi Tlusty
Life relies on the efficient performance of molecular codes, which relate symbols and meanings via error-prone molecular recognition. We describe how optimizing a code to withstand…