3 citations · 3 across the 3 of their papers we have counts for
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Mechanism, scaling and rates of protein aggregation from in vivo measurements
Georg Meisl, Alexander J Dear, Thomas CT Michaels +1
The formation and proliferation of protein aggregates play a central role in a number of devastating neuro-degenerative diseases. Many experimental studies indicate that the abilit…
Reaction rate theory for supramolecular kinetics: application to protein aggregation
Thomas C. T. Michaels, Lucie X. Liu, Samo Curk +3
Probing the reaction mechanisms of supramolecular processes in soft- and biological matter, such as protein aggregation, is inherently challenging. These processes emerge from the…
Nucleated polymerisation in the presence of pre-formed seed filaments
Samuel I. A. Cohen, Michele Vendruscolo, Christopher M. Dobson +1
We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting c…