3 citations · 3 across the 3 of their papers we have counts for
5 papers
Hamiltonian Dynamics of Saturated Elongation in Amyloid Fiber Formation
Liu Hong, Xizhou Liu, Thomas C. T. Michaels +1
Elongation is a fundament process in amyloid fiber growth, which is normally characterized by a linear relationship between the fiber elongation rate and the monomer concentration.…
The role of clearance mechanisms in the kinetics of toxic protein aggregates involved in neurodegenerative diseases
Travis B. Thompson, Georg Meisl, Tuomas Knowles +1
Protein aggregates in the brain play a central role in cognitive decline and structural damage associated with neurodegenerative diseases. For instance, in Alzheimer's disease the…
Mechanism, scaling and rates of protein aggregation from in vivo measurements
Georg Meisl, Alexander J Dear, Thomas CT Michaels +1
The formation and proliferation of protein aggregates play a central role in a number of devastating neuro-degenerative diseases. Many experimental studies indicate that the abilit…
Reaction rate theory for supramolecular kinetics: application to protein aggregation
Thomas C. T. Michaels, Lucie X. Liu, Samo Curk +3
Probing the reaction mechanisms of supramolecular processes in soft- and biological matter, such as protein aggregation, is inherently challenging. These processes emerge from the…
Nucleated polymerisation in the presence of pre-formed seed filaments
Samuel I. A. Cohen, Michele Vendruscolo, Christopher M. Dobson +1
We revisit the classical problem of nucleated polymerisation and derive a range of exact results describing polymerisation in systems intermediate between the well-known limiting c…