most citedSANA: Cross-Species Prediction of Gene Ontology GO Annotations via Topological Network Alignment

13 citations · 18 across the 6 of their papers we have counts for

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q-bio.MN2023

New GO-based Measures and Their Statistical Significance in Multiple Network Alignment

Reza Mousapour, Kimia Yazdani, Wayne B. Hayes

Protein-protein interaction (PPI) networks provide valuable insights into the function of biological systems, and aligning multiple PPI networks can reveal important functional rel…

q-bio.MN2022

BLANT: Basic Local Alignment of Network Topology, Part 1: Seeding local alignments with unambiguous 8-node graphlets

Patrick Wang, Henry Ye, Wayne B Hayes

BLAST is a standard tool in bioinformatics for creating local sequence alignments using a "seed-and-extend" approach. Here we introduce an analogous seed-and-extend algorithm that…

q-bio.MN2022

BLANT: Basic Local Alignment of Network Topology, Part 2: Topology-only Extension Beyond Graphlet Seeds

Tingyin Ding, Utsav Jain, Wayne B. Hayes

BLAST is a standard tool in bioinformatics for creating local sequence alignments using a "seed-and-extend" approach. Here we introduce an analogous seed-and-extend algorithm that…

q-bio.MN2022★ 13 cited

SANA: Cross-Species Prediction of Gene Ontology GO Annotations via Topological Network Alignment

Siyue Wang, Giles R. S. Atkinson, Wayne B. Hayes

Topological network alignment aims to align two networks node-wise in order to maximize the observed common connection (edge) topology between them. The topological alignment of tw…

q-bio.MN2022★ 5 cited

On the current failure -- but bright future -- of topology-driven biological network alignment

Siyue Wang, Xiaoyin Chen, Brent J. Frederisy +4

The function of a protein is defined by its interaction partners. Thus, topology-driven network alignment of the protein-protein interaction (PPI) networks of two species should un…