most citedSANA: Cross-Species Prediction of Gene Ontology GO Annotations via Topological Network Alignment

13 citations · 18 across the 6 of their papers we have counts for

collaborators

6 papers

q-bio.MN2023

New GO-based Measures and Their Statistical Significance in Multiple Network Alignment

Reza Mousapour, Kimia Yazdani, Wayne B. Hayes

Protein-protein interaction (PPI) networks provide valuable insights into the function of biological systems, and aligning multiple PPI networks can reveal important functional rel…

cs.SI2022

Detection of large exact subgraph isomorphisms with a topology-only graphlet index built using deterministic walks

Patrick Wang, Henry Ye, Wayne Hayes

We introduce the first algorithm to perform topology-only local graph matching (a.k.a. local network alignment or subgraph isomorphism): BLANT, for Basic Local Alignment of Network…

q-bio.MN2022

BLANT: Basic Local Alignment of Network Topology, Part 1: Seeding local alignments with unambiguous 8-node graphlets

Patrick Wang, Henry Ye, Wayne B Hayes

BLAST is a standard tool in bioinformatics for creating local sequence alignments using a "seed-and-extend" approach. Here we introduce an analogous seed-and-extend algorithm that…

q-bio.MN2022

BLANT: Basic Local Alignment of Network Topology, Part 2: Topology-only Extension Beyond Graphlet Seeds

Tingyin Ding, Utsav Jain, Wayne B. Hayes

BLAST is a standard tool in bioinformatics for creating local sequence alignments using a "seed-and-extend" approach. Here we introduce an analogous seed-and-extend algorithm that…

q-bio.MN2022★ 13 cited

SANA: Cross-Species Prediction of Gene Ontology GO Annotations via Topological Network Alignment

Siyue Wang, Giles R. S. Atkinson, Wayne B. Hayes

Topological network alignment aims to align two networks node-wise in order to maximize the observed common connection (edge) topology between them. The topological alignment of tw…

q-bio.MN2022★ 5 cited

On the current failure -- but bright future -- of topology-driven biological network alignment

Siyue Wang, Xiaoyin Chen, Brent J. Frederisy +4

The function of a protein is defined by its interaction partners. Thus, topology-driven network alignment of the protein-protein interaction (PPI) networks of two species should un…