134 citations · 294 across the 15 of their papers we have counts for
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stat.AP2022
Oncology Dose Finding Using Approximate Bayesian Computation Design
Huaqing Jin, Wenbin Du, Guosheng Yin
In the development of new cancer treatment, an essential step is to determine the maximum tolerated dose (MTD) via phase I clinical trials. Generally speaking, phase I trial design…
stat.AP2014★ 75 cited
Bayesian data augmentation dose finding with continual reassessment method and delayed toxicity
Suyu Liu, Guosheng Yin, Ying Yuan
A major practical impediment when implementing adaptive dose-finding designs is that the toxicity outcome used by the decision rules may not be observed shortly after the initiatio…
stat.AP2011★ 73 cited
Bayesian phase I/II adaptively randomized oncology trials with combined drugs
Ying Yuan, Guosheng Yin
We propose a new integrated phase I/II trial design to identify the most efficacious dose combination that also satisfies certain safety requirements for drug-combination trials. W…