45 citations · 112 across the 5 of their papers we have counts for
5 papers
Kinetic limitations of cooperativity based drug delivery systems
Nicholas A. Licata, Alexei V. Tkachenko
We study theoretically a novel drug delivery system that utilizes the overexpression of certain proteins in cancerous cells for cell specific chemotherapy. The system consists of d…
Elasticity of strongly stretched ssDNA
Alexei V. Tkachenko
We present a simple model which describes elastic response of single-stranded DNA (ssDNA) to stretching, including the regime of very high force (up to 1000 pN). ssDNA is modelled…
Colloids with key-lock interactions: non-exponential relaxation, aging and anomalous diffusion
Nicholas A. Licata, Alexei V. Tkachenko
The dynamics of particles interacting by key-lock binding of attached biomolecules are studied theoretically. Experimental realizations of such systems include colloids grafted wit…
Statistical Mechanics of DNA-Mediated Colloidal Aggregation
Nicholas A. Licata, Alexei V. Tkachenko
We present a statistical mechanical model of aggregation in colloidal systems with DNA mediated interactions. We obtain a general result for the two-particle binding energy in term…
Self-assembly of DNA-coded nanoclusters
Nicholas A. Licata, Alexei V. Tkachenko
We present a theoretical discussion of a self-assembly scheme which makes it possible to use DNA to uniquely encode the composition and structure of micro- and nanoparticle cluster…