69 citations · 207 across the 7 of their papers we have counts for
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q-bio.MN2015★ 15 cited
Phenotypic spandrel: absolute discrimination and ligand antagonism
Paul François, Mathieu Hemery, Kyle A. Johnson +1
We consider the general problem of sensitive and specific discrimination between biochemical species. An important instance is immune discrimination between self and not-self, wher…
q-bio.MN2013★ 48 cited
Principles of Adaptive Sorting Revealed by In Silico Evolution
Jean-Benoît Lalanne, Paul François
Many biological networks have to filter out useful information from a vast excess of spurious interactions. We use computational evolution to predict design features of networks pr…
q-bio.MN2005★ 69 cited
A core genetic module : the Mixed Feedback Loop
Paul Francois, Vincent Hakim
The so-called Mixed Feedback Loop (MFL) is a small two-gene network where protein A regulates the transcription of protein B and the two proteins form a heterodimer. It has been fo…