3 papers
stat.ME2024
Online robust estimation and bootstrap inference for function-on-scalar regression
Guanghui Cheng, Wenjuan Hu, Ruitao Lin +1
We propose a novel and robust online function-on-scalar regression technique via geometric median to learn associations between functional responses and scalar covariates based on…
stat.AP2024
DEMO: Dose Exploration, Monitoring, and Optimization Using a Biological Mediator for Clinical Outcomes
Cheng-Han Yang, Peter F. Thall, Ruitao Lin
Phase 1-2 designs provide a methodological advance over phase 1 designs for dose finding by using both clinical response and toxicity. A phase 1-2 trial still may fail to select a…
stat.ME2020
Mixture of Finite Mixtures Model for Basket Trial
Junxian Geng, Tianjian Zhou, Ruitao Lin +1
With the recent paradigm shift from cytotoxic drugs to new generation of target therapy and immuno-oncology therapy during oncology drug developments, patients with various cancer…