331 citations · 612 across the 10 of their papers we have counts for
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Imaging Dynamic Microtubules and Associated Proteins by Simultaneous Interference-Reflection and Total-Internal-Reflection-Fluorescence Microscopy
Yazgan Tuna, Amer Al-Hiyasat, Jonathon Howard
Several techniques have been employed for the direct visualization of cytoskeletal filaments and their associated proteins. Total-internal-reflection-fluorescence (TIRF) microscopy…
Herding of proteins by the ends of shrinking polymers
Amer Al-Hiyasat, Yazgan Tuna, Yin-Wei Kuo +1
The control of biopolymer length is mediated by proteins that localize to polymer ends and regulate polymerization dynamics. Several mechanisms have been proposed to achieve end lo…
Ciliary beating patterns map onto a low-dimensional behavioral space that accords with a simple mechanochemical model
Veikko Geyer, Jonathon Howard, Pablo Sartori
Biological systems are robust to perturbations at both the genetic and environmental levels. Yet, these same perturbations can elicit variation in behavior. The interplay between f…
Dynamic curvature regulation accounts for the symmetric and asymmetric beats of Chlamydomonas flagella
Pablo Sartori, Veikko Geyer, Andre Scholich +2
Axonemal dyneins are the molecular motors responsible for the beating of cilia and flagella. These motors generate sliding forces between adjacent microtubule doublets within the a…
Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs
V. Mukundan, P. Sartori, V. F. Geyer +2
The bending of cilia and flagella is driven by forces generated by dynein motor proteins. These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskelet…
Calibration of optical tweezers with positional detection in the back-focal-plane
Simon F. Tolic-Norrelykke, Erik Schaeffer, Jonathon Howard +3
We explain and demonstrate a new method of force- and position-calibration for optical tweezers with back-focal-plane photo detection. The method combines power spectral measuremen…