Showing 2026Show all
2 papers · 1 filter
cs.LG2026
Constraint-Aware Flow Matching: Decision Aligned End-to-End Training for Constrained Sampling
Jacob K. Christopher, James E. Warner, Ferdinando Fioretto
Deep generative models provide state-of-the-art performance across a wide array of applications, with recent studies showing increasing applicability for science and engineering. D…
q-bio.BM2026
Constrained Diffusion for Protein Design with Hard Structural Constraints
Jacob K. Christopher, Austin Seamann, Jingyi Cui +2
Diffusion models offer a powerful means of capturing the manifold of realistic protein structures, enabling rapid design for protein engineering tasks. However, existing approaches…