activity
20062022
most citedA variational approach to the stochastic aspects of cellular signal transduction

36 citations · 179 across the 13 of their papers we have counts for

collaborators

13 papers

cond-mat.soft2022★ 4 cited

On Stretching, Bending, Shearing and Twisting of Actin Filaments II: Multi-Resolution Modelling

Ravinda Gunaratne, Carlos Floyd, Haoran Ni +2

We present a multi-resolution methodology for modelling F-actin filaments. It provides detailed microscopic information at the level of individual monomers at a lower computational…

cond-mat.soft2021

On Stretching, Bending, Shearing and Twisting of Actin Filaments I: Variational Models

Carlos Floyd, Haoran Ni, Ravinda S. Gunaratne +2

Mechanochemical simulations of actomyosin networks are traditionally based on one-dimensional models of actin filaments having zero width. Here, and in the follow up paper, approac…

q-bio.QM2021★ 18 cited

Actin reorganization throughout the cell cycle mediated by motor proteins

Maria-Veronica Ciocanel, Aravind Chandrasekaran, Carli Mager +3

Cortical actin networks are highly dynamic and play critical roles in shaping the mechanical properties of cells. The actin cytoskeleton undergoes significant reorganization over t…

cond-mat.soft2021★ 8 cited

Segmental Lennard-Jones Interactions for Semi-flexible Polymer Networks

Carlos Floyd, Aravind Chandrasekaran, Haoran Ni +2

Simulating soft matter systems such as the cytoskeleton can enable deep understanding of experimentally observed phenomena. One challenge of modeling such systems is realistic desc…

physics.bio-ph2020★ 16 cited

Understanding cytoskeletal avalanches using mechanical stability analysis

Carlos Floyd, Herbert Levine, Christopher Jarzynski +1

Eukaryotic cells are mechanically supported by a polymer network called the cytoskeleton, which consumes chemical energy to dynamically remodel its structure. Recent experiments in…

physics.bio-ph2019★ 14 cited

Minimal Cylinder Analysis Reveals the Mechanical Properties of Oncogenic Nucleosomes

Mary Pitman, Yamini Dalal, Garegin A. Papoian

Histone variants regulate replication, transcription, DNA damage repair, and chromosome segregation. Though widely accepted as a paradigm, it has not been rigorously demonstrated t…