56 citations · 149 across the 8 of their papers we have counts for
3 papers · 1 filter
Exact solution of stochastic gene expression models with bursting, cell cycle and replication dynamics
Casper H. L. Beentjes, Ruben Perez-Carrasco, Ramon Grima
The bulk of stochastic gene expression models in the literature do not have an explicit description of the age of a cell within a generation and hence they cannot capture events su…
Stochastic modeling of auto-regulatory genetic feedback loops: a review and comparative study
James Holehouse, Zhixing Cao, Ramon Grima
Auto-regulatory feedback loops are one of the most common network motifs. A wide variety of stochastic models have been constructed to understand how the fluctuations in protein nu…
Parameter estimation for biochemical reaction networks using Wasserstein distances
Kaan Öcal, Ramon Grima, Guido Sanguinetti
We present a method for estimating parameters in stochastic models of biochemical reaction networks by fitting steady-state distributions using Wasserstein distances. We simulate a…