4 papers · 1 filter
Reliable mechanistic operator recovery with biologically-informed neural networks: principles for architecture and optimisation design
Rebecca M. Crossley, Yuan Yin, Sarah L. Waters +1
Many biological processes are governed by complex dynamical mechanisms that remain incompletely understood despite increasing volumes of experimental data. Biologically-informed ne…
Optimal control of collective electrotaxis in epithelial monolayers
Simon F. Martina-Perez, Isaac B. Breinyn, Daniel J. Cohen +1
Epithelial monolayers are some of the best-studied models for collective cell migration due to their abundance in multicellular systems and their tractability. Experimentally, the…
Quantifying cell cycle regulation by tissue crowding
Carles Falcó, Daniel J. Cohen, José A. Carrillo +1
The spatiotemporal coordination and regulation of cell proliferation is fundamental in many aspects of development and tissue maintenance. Cells have the ability to adapt their div…
Structural identifiability analysis of linear reaction-advection-diffusion processes in mathematical biology
Alexander P Browning, Maria Tască, Carles Falcó +1
Effective application of mathematical models to interpret biological data and make accurate predictions often requires that model parameters are identifiable. Approaches to assess…