3 citations · 3 across the 9 of their papers we have counts for
9 papers
Cell-cell adhesion cannot sustain extended follower streams in a minimal non-local model of leader-follower migration
Thomas Jun Jewell, Samuel W. S. Johnson, Ruth E. Baker +1
Cell-cell adhesion is widely hypothesised to maintain cohesion within the long streams of follower cells that trail leader subpopulations during collective migration, including in…
The spontaneous emergence of leaders and followers in a mathematical model of cranial neural crest cell migration
Samuel W. S. Johnson, Ruth E. Baker, Philip K. Maini
Many agent-based mathematical models of cranial neural crest cell (CNCC) migration impose a binary phenotypic partition of cells into either leaders or followers. In such models, t…
An energy-based mathematical model of actin-driven protrusions in eukaryotic chemotaxis
Samuel W. S. Johnson, Maddy Parsons, Ruth E. Baker +1
In eukaryotic cell chemotaxis, cells extend and retract transient actin-driven protrusions at their membrane that facilitate both the detection of external chemical gradients and d…
Spatial correlations in SIS processes on random regular graphs
Alexander Leibenzon, Samuel W. S. Johnson, Ruth E. Baker +1
In network-based SIS models of infectious disease transmission, infection can only occur between directly connected individuals. This constraint naturally gives rise to spatial cor…
Optimal experiment design for practical parameter identifiability and model discrimination
Yue Liu, Philip K. Maini, Ruth E. Baker
Mechanistic mathematical models of biological systems usually contain a number of unknown parameters whose values need to be estimated from available experimental data in order for…
Modelling the impact of phenotypic heterogeneity on cell migration: a continuum framework derived from individual-based principles
Rebecca M. Crossley, Philip K. Maini, Ruth E. Baker
Collective cell migration plays a crucial role in numerous biological processes, including tumour growth, wound healing, and the immune response. Often, the migrating population co…
Collective Invasion: When does domain curvature matter?
Joseph J. Pollacco, Ruth E. Baker, Philip K. Maini
Real-world cellular invasion processes often take place in curved geometries. Such problems are frequently simplified in models to neglect the curved geometry in favour of computat…
Phenotypic switching mechanisms determine the structure of cell migration into extracellular matrix under the `go-or-grow' hypothesis
Rebecca M. Crossley, Kevin J. Painter, Tommaso Lorenzi +2
A fundamental feature of collective cell migration is phenotypic heterogeneity which, for example, influences tumour progression and relapse. While current mathematical models ofte…
Parameter identifiability and model selection for partial differential equation models of cell invasion
Yue Liu, Kevin Suh, Philip K. Maini +2
When employing mechanistic models to study biological phenomena, practical parameter identifiability is important for making accurate predictions across wide range of unseen scenar…