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q-bio.CB2024
Collective Invasion: When does domain curvature matter?
Joseph J. Pollacco, Ruth E. Baker, Philip K. Maini
Real-world cellular invasion processes often take place in curved geometries. Such problems are frequently simplified in models to neglect the curved geometry in favour of computat…
q-bio.CB2024
Phenotypic switching mechanisms determine the structure of cell migration into extracellular matrix under the `go-or-grow' hypothesis
Rebecca M. Crossley, Kevin J. Painter, Tommaso Lorenzi +2
A fundamental feature of collective cell migration is phenotypic heterogeneity which, for example, influences tumour progression and relapse. While current mathematical models ofte…