activity
20062024
most citedTwo General Methods for Population Pharmacokinetic Modeling: Non-Parametric Adaptive Grid and Non-Parametric Bayesian

82 citations · 199 across the 24 of their papers we have counts for

collaborators
Showing 2011Show all

10 papers · 1 filter

math.ST2011

A New Characterization of Elfving's Method for High Dimensional Computation

Jay Bartroff

We give a new characterization of Elfving's (1952) method for computing c-optimal designs in k dimensions which gives explicit formulae for the k unknown optimal weights and k unkn…

stat.ME2011

Incorporating Individual and Collective Ethics into Phase I Cancer Trial Designs

Jay Bartroff, Tze Leung Lai

A general framework is proposed for Bayesian model-based designs of Phase I cancer trials, in which a general criterion for coherence (Cheung, 2005) of a design is also developed.…

math.PR2011

The Fighter Problem: Optimal Allocation of a Discrete Commodity

Jay Bartroff, Ester Samuel-Cahn

The Fighter problem with discrete ammunition is studied. An aircraft (fighter) equipped with anti-aircraft missiles is intercepted by enemy airplanes, the appearance of which f…

stat.ME2011

Multistage tests of multiple hypotheses

Jay Bartroff, Tze Leung Lai

Conventional multiple hypothesis tests use step-up, step-down, or closed testing methods to control the overall error rates. We will discuss marrying these methods with adaptive mu…

stat.ME2011★ 43 cited

Modern Sequential Analysis and its Applications to Computerized Adaptive Testing

Jay Bartroff, Matthew Finkelman, Tze Leung Lai

After a brief review of recent advances in sequential analysis involving sequential generalized likelihood ratio tests, we discuss their use in psychometric testing and extend the…

math.ST2011

Generalized Likelihood Ratio Statistics and Uncertainty Adjustments in Efficient Adaptive Design of Clinical Trials

Jay Bartroff, Tze Leung Lai

A new approach to adaptive design of clinical trials is proposed in a general multiparameter exponential family setting, based on generalized likelihood ratio statistics and optima…